Concern

By way of your final response.

That is my time that is second I this concern.

I have re-done a comprehensive research about the physiology of male genitalia. Simply speaking, as it happens that information out there was inconsistent. In Wikipedia, two split entries of Foreskin’ and Mucous membrane’ yield contradictory outcomes: the previous claims the glans penis (head of this penis) and glans clitoridis plus the inside the prepuce (foreskin) and hood that is clitoral maybe perhaps not mucous membranes’, as the latter says that the internal foreskin is a mucous membrane layer just like the inside the eyelid or perhaps the lips. ‘ in addition, relating to glans penis’ of wikipedia, The epithelium of this glans penis is mucocutaneous muscle.’

Because of the means we discovered that the foreskin consists of Langerhans cells that are recognized as receptor of HIV virus (these records arises from OU Handbook of GUM and HIV medicine).

I’ve talked about these problems with a psychiatrist (this is because i’m i am excessively concerned within the whole HIV/STD thingy) who warned me personally that I shouldn’t be doing penis-to-penis side-along rubbing and penis docking more because `it’s rubbing of mucosal cells. HIV/STD virus is likely to pass between. Why can you just take such risks?’

In your final response (response that is last), you said that the transmission danger of dick-docking is actually nonexistent and implied that penis-to-penis side-along rubbing does perhaps perhaps maybe not pose any transmission danger since the only mucous membrane layer for the entire cock (including shaft, foreskin, glans penis) could be the lining for the urethra through the pee-hole up into the bladder. But i did not point out that I’m uncircumcised. There is an abundance of inner foreskin whose really nature is extremely dubious of mucous membrane layer and which can be high in Langerhans cells.

Therefore my questions are: (1) would you please reiterate your viewpoint regarding the transmission threat of dick-docking and penis-to-penis rubbing that is side-along citing the real reason for?? let’s say certainly one of us shot the strain? Would the strain shoot right at the urethra during docking. (2) should we put a condom on although we do dick-docking and penis-to-penis side-along rubbing? (3) must I perform a circumcision, as some studies from Kenya(!) recommend it decreases the possibility of transmission of HIV along with other STDs? Do it is believed by you?? (4) why are Langerhans cells cited as vunerable to HIV infection? Just exactly What part does it play ?? (5) how come the definition of membrane that is `mucous so essential in HIV illness? What exactly is it anyhow?? Would HIV or other STDs chat hour mobile have throughout the membrane layer and infect other people??

As bothersome as i’m, we sincerely do hope that you’dn’t find my inquiries unpleasant or devious by any means. Debate results in better understanding. If you wish you painstakingly answer my questions? for me to have some sort of peace, could?

I vow We shall donate USD150 to your charity fund.

Response

My estimation regarding HIV transmission/acquisition associated to frottage (penis-to-penis rubbing, “dick-docking”) remains unchanged. It is really not regarded as being a danger. Could a load is shot by you and strike the urethra? Yes, it is theoretically possible, while not more than likely, that the spunk would in fact enter into significant connection with the urethra’s mucous membrane layer.

If that would make you are feeling safer much less anxious, yes. Really, I do not feel it is necessary.

The studies do indicate that male circumcision decreases the chance for acquiring HIV. But, in the event that you follow safer intimate strategies, I do not feel it is necessary.

Langerhan’s cells (dendritic cells) perform a essential part in the initiation of HIV illness by virtue regarding the cap cap cap ability of HIV to bind to certain mobile area receptors of the cells. This enables efficient presentation of HIV to CD4 cells that then become contaminated. The foreskin contains Langerhan’s cells.

A membrane that is mucous a thin layer (membrane layer) that lines all interior human anatomy passages that communicate straight with atmosphere beyond your human body, like the respiratory and alimentary tracts, and that has specialized cells or glands that secrete mucous. HIV can permeate mucous membranes, nonetheless it cannot permeate skin that is intact. The foreskin just isn’t a membrane that is mucous. Nevertheless, it really is a type that is specialized of and HIV may be taken on by the Langerhan’s (dendritic) cells positioned inside the foreskin.

We truly do not find your inquiries either devious or”offensive.” It may be somewhat confusing to attempt to explain complex information on structure or perhaps the purpose of specific cells in a forum similar to this forum. And so the physiology course has ended for today.